Hypostatic gene

 ( Classical Genetics ) 

A hypostatic gene is one whose phenotype is altered by the expression of an allele at a separate locus, in an epistasis event.

Example: In labrador retrievers, the chocolate coat colour is a result of Zygosity for a gene that is epistasis to the "black vs. brown" gene. The alleles determining whether the dog is black or brown, are that of the hypostatic gene in this event.

• Epistasis
• Bombay phenotype